Question

Soluble fibrinogen is converted into insoluble fibrin by the action of :

Answer 1

Thrombin acts as an enzyme and first brings about depolymerization of fibrinogen (a soluble type of plasma protein) into its own specific monomers. Later Thrombin stimulates repolymerization of these monomers into long insoluble fibre-like polymers called fibrin. Finally, the thin, long and insoluble form of solid fibres of fibrin of form a dense network upon the wound and trap blood corpuscles (RBCs, WBCs and platelets) to form a clot . The clot seals the wound and stops bleeding.