Structure and function of dna polymerase 3
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Function of DNA Polymerase. ... In order for the nucleotides to be exposed, DNA helicase comes in and unwinds the DNA by breaking the hydrogen bonds that hold the two strands together. This allows the nucleotides on both strands ofDNA to be read and used as templates by DNA polymerase.
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DNA Pol 3 is a multi-subunit enzyme.it consisted of alpha subunits,beta dimerspl and epsilon subunits.The alpha and epsilon subunits form the core enzyme.
Alpha subunit does polymerization activity.
The beta dimers acts as beta clamp and help in replication of the lagging strand.
The epsilon subunit does proof reading activity from 3 prime to 5 prime direction.
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