Question

Structure of nucleotide and nucleoside and its structure difference with

Answer 1

A nucleoside consists of a nitrogenous base covalently attached to a sugar (ribose or deoxyribose) but without the phosphate group. A nucleotide consists of a nitrogenous base, a sugar (ribose or deoxyribose) and one to three phosphate groups.

Nucleoside = Sugar + Base 
Nucleotide = Sugar + Base + Phosphate

Comparison chart

Nucleoside versus Nucleotide comparison chartNucleosideNucleotideChemical CompositionSugar + Base. A nucleoside consists of a nitrogenous base covalently attached to a sugar (ribose or deoxyribose) but without the phosphate group. When phosphate group of nucleotide is removed by hydrolysis, the structure remaining is nucleoside.Sugar + Base + Phosphate. A nucleotide consists of a nitrogenous base, a sugar (ribose or deoxyribose) and one to three phosphate groups.Relevance in medicineSeveral nucleoside analogues are used as antiviral or anticancer agents.Malfunctioning nucleotides are one of the main causes of all cancers known of today.ExamplesExamples of nucleosides include cytidine, uridine, adenosine, guanosine, thymidine and inosine.Nucleotides follow the same names as nucleosides, but with the indication of phosphate groups. For example, 5'-uridine monophosphate.

Answer 2

Answer:

Nucleosides are the structural subunit of nucleic acids such as DNA and RNA. Nucleotides are composed of a nitrogenous base, a five-carbon sugar (ribose or deoxyribose), and at least one phosphate group. ... Thus a nucleoside plus a phosphate group yields a nucleotide.