Substitution of methanol in conjugated vinyl chloride
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Answer:
Primary mechanism of detoxification of vinyl chloride or its reactive metabolites involves conjugation with hepatic glutathione.
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Explanation:
Vinyl chloride (CH2=CHCl) is unreactive in nucleophilic substitution reaction due to resonance. In vinyl chloride, the lone pair of electrons on chlorine is in resonance with the C-C double bond, because of which there is partial double bond character in C-Cl bond.
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