Question

Substitution of methanol in conjugated vinyl chloride

Answer 1

Answer:

Primary mechanism of detoxification of vinyl chloride or its reactive metabolites involves conjugation with hepatic glutathione.

Answer 2

Explanation:

Vinyl chloride (CH2=CHCl) is unreactive in nucleophilic substitution reaction due to resonance. In vinyl chloride, the lone pair of electrons on chlorine is in resonance with the C-C double bond, because of which there is partial double bond character in C-Cl bond.