Question

Technique used for capturing specific target proteins and mapping their binding epitope containing peptide.
1. Lin’s technique
2. Brown’s technique
3. Fen’s technique
4. Mark’s technique

Answer 1

Answer:

lin

Explanation:

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Answer 2

Option A is the correct answer

Lin’s technique

Explanation:

• Epitope mapping is the process of empirically determining an antibody's binding location, or "epitope," on its intended antigen (usually, on a protein).
• New treatments, vaccines, and diagnostics can be developed and discovered thanks to the identification and characterization of antibody binding sites.
• Characterizing an epitope can assist clarify how an antibody binds, as well as increase the protection of intellectual property (patents).
• Robust algorithms can use experimental epitope mapping data to enable in silico prediction of B-cell epitopes based on sequence and/or structural data.
• The two main categories of epitopes are linear and conformational. A protein's amino acid sequence that runs continuously creates linear epitopes.
• While the amino acid sequence of a protein is continuous, conformational epitopes are made up of amino acids that are brought together during three-dimensional protein folding.
• According to B-cell epitope mapping research, the majority of interactions between antigens and antibodies—particularly autoantibodies and protective antibodies rely on binding to conformational epitopes.

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