The formation of phosphodiester bonds between two nucleotides can be considered as
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The phosphodiester bond links a 3' carbon to a 5' carbon in DNA and RNA. During the reaction of two of the hydroxyl groups in phosphoric acid with a hydroxyl group in two other molecules two ester bonds in aphosphodiester group are formed. ... The links between the nucleotides arecalled phosphodiester bonds.
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A DNA ligase re-forms phosphodiester bonds between adjacent nucleotides. The ligation reaction links the deoxyribose-phosphate rails of the fragments into a stable double helix. This ligation reaction is another example of a condensation reaction
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