The inheritance of two genctic diseases namely
phenylketonuria and haemophilia are to be studied
in two different individuals. Both these studies
will involve the use of :-
(1) Autosomes
(2) Sex chromosomes
(3) Restriction endonuclease
(4) Pedigree analysis
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Let the dominant allele be 'A' and let the recessive allele be 'a'.
(a) Member 4 could be Aa (carrier) or aa (unaffected).
Member 5 is aa (affected).
Member 6 could be Aa (carrier) or aa (unaffected).
(b) Member 14 is a carrier female which means the genotype is Aa. Member 15 is an unaffected male (AA). So, the probability that the first child is a haemophilic male is 1/4
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