The major advantage of using artificialchromosomes such as yacs and bacs for cloning genes is that
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BAC (Bacterial Artificial Chromosome) G.M. Weinstock, in Encyclopedia of Genetics, 2001. Bacterial artificial chromosomes (BACs) are plasmids used for cloning and stably maintaining large segments of foreign DNA in Escherichia coli. This is important in various types of analyses of mammalian and other genomes.
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