Question

the net gain of atp molecules during aerobic breakdown of one glucose molecule is​

Answer 1

for the glucose molecule to oxidize the into pyruvate, an input of ATP molecule is required this is known as investment phase, in which a total of 2 ATP molecules are consumed at the end of glycolysis the total yield of ATP is 4 molecules but the net gain is 2 ATP molecules

Answer 2

In aerobic conditions, the process converts one molecule of glucose into two molecules of pyruvate (pyruvic acid), generating energy in the form of two net molecules of ATP. Four molecules of ATP per glucose are actually produced, however, two are consumed as part of the preparatory phase.