Question

the thalidomide tragedy is consumption of drug
(a) analgesic
(b) steroidal
(c) sedative
(d) sulpha​

Answer 1

Answer:

Thalidomide, sold under the brand names Contergan and Thalomid among others, is a medication used to treat a number of cancers (including multiple myeloma), graft-versus-host disease, and a number of skin conditions including complications of leprosy.[3] While it has been used in a number of HIV-associated conditions, such use is associated with increased levels of the virus.[3] It is administered orally.[3]

ThalidomideClinical dataPronunciation/θəˈlɪdəmaɪd/[1]Trade namesContergan, Thalomid, Talidex, othersOther namesα-PhthalimidoglutarimideAHFS/Drugs.comMonographMedlinePlusa699032License data

Pharmacokinetic dataBioavailability90%Protein binding55% and 66% for the (R)-(+)- and (S)-(−)-enantiomers, respectively[2]MetabolismLiver (minimally via CYP2C19-mediated 5-hydroxylation; mostly via non-enzymatic hydrolysis at the four amide sites)[2]Elimination half-life5–7.5 hours (dose-dependent)[2]ExcretionUrine,

Common side effects include sleepiness, rash, and dizziness.[3] Severe side effects include tumor lysis syndrome, blood clots, and peripheral neuropathy.[4] Use in pregnancy may harm the baby, including resulting in malformation of the limbs.[3] In males who are taking the medication, contraception is essential if the partner could become pregnant.[4] It is an immunomodulatory medication and works by a number of mechanisms including stimulating