Question

VEGFR, a receptor tyrosine kinase, is required for the formation of new blood vessels.
Activity of VEGFR-mediated signaling is often high in tumors, enabling them to obtain the
nutrients necessary for growth. Which of the following would be the best therapeutic strategy
for inhibiting VEGFR-mediated signaling?
A) GTPγS, a non-hydrolyzable analogue of GTP
B) A drug that inhibits calmodulin
C) A drug that inhibits this pathway’s GAP
D) A drug that inhibits this pathway’s GEF
E) A drug that inhibits the receptor’s phosphatase

Answer 1

Answer:

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Explanation:

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