Question

Vinka alkaloids exert antitumor
activity by​

Answer 1

Answer:

Vinca alkaloids are cell-cycle specific in the M phase. They exert their antitumor effect by binding to microtubular proteins and inhibiting the polymerization of tubulin, which leads to the disruption of the microtubule assembly during mitosis and to the metaphase arrest of the cell (Moudi, Go, Yien, & Nazre, 2013).

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