Question

what are lysosomes and how are they formed?

Answer 1

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Answer 2

Lysosomes are spherical membranous sacs of enzymes. These enzymes are acidic hydrolase enzymes that can digest cellular macromolecules. The lysosome membrane helps to keep its internal compartment acidic and separates the digestive enzymes from the rest of the cell. Lysosome enzymes are made by proteins from the endoplasmic reticulum and enclosed within vesicles by the Golgi apparatus. Lysosomes are formed by budding from the Golgi complex.


Lysosomes are formed from the fusion of vesicles from the Golgi complex with endosomes. Endosomes are vesicles that are formed by endocytosis as a section of the plasma membrane pinches off and is internalized by the cell. In this process, extracellular material is taken up by the cell. As endosomes mature, they become known as late endosomes. Late endosomes fuse with transport vesicles from the Golgi that contain acid hydrolases. Once fused, these endosomes eventually develop into lysosomes.

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