what are nodes of ranvier ??
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- The Node of Ranvier is the 1-2 micrometre gap between the glial cells of the myelin sheath.
- These glial cells are called Schwann cells, and they help to electrically insulate the neuron.
- The Nodes of Ranvier are only present when the axon of a neuron is myelinated.
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Nodes of Ranvier also known as myelin-sheath gaps occur along a myelinated axon where the axolemma is exposed to the extracellular space. Nodes of ranvier are uninsulated and highly enriched in ion channels, allowing them to participate in the exchange of ions required to regenerate action potential.
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