Question

What are some problems that can occur from an altered gene that makes hemoglobin?

Answer 1

Answer:

The most common is the development of sickle cell anemia. This is a result of a mutation in the hemoglobin gene that affects the beta polypeptide chain of the protein. This reduces HB's affinity to oxygen. Other problems include Thalassaemia, Porphyria, and Carbon Monoxide Poisoning.

Answer 2

Answer:

If mutations that produce hemoglobin S and beta thalassemia occur together, individuals have hemoglobin S-beta thalassemia (HbSBetaThal) disease. Abnormal versions of beta-globin can distort red blood cells into a sickle shape. The sickle-shaped red blood cells die prematurely, which can lead to anemia.

The most common is the development of sickle cell anemia. This is as a result of a mutation in the hemoglobin gene that affects the beta polypeptide chain of the protein. This reduces HB's affinity to oxygen. Other problems include Thalassaemia, Porphyria, and Carbon Monoxide Poisoning.

People who have these forms of SCD inherit one sickle cell gene (“S”) and one gene from an abnormal type of hemoglobin (“D”, “E”, or “O”). Hemoglobin is a protein that allows red blood cells to carry oxygen to all parts of the body. The severity of these rarer types of SCD

Explanation:

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