What are the biological factors that carry genetic properties from generation to generation?
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The classical principles of genetics were deduced by Gregor Mendel in 1865, on the basis of the results of breeding experiments with peas. Mendel studied the inheritance of a number of well-defined traits, such as seed color, and was able to deduce general rules for their transmission. In all cases, he could correctly interpret the observed patterns of inheritance by assuming that each trait is determined by a pair of inherited factors, which are now called genes. One gene copy (called an allele) specifying each trait is inherited from each parent. For example, breeding two strains of peas—one having yellow seeds, and the other green seeds—yields the following results (Figure 3.1). The parental strains each have two identical copies of the gene specifying yellow (Y) or green (y) seeds, respectively. The progeny plants are therefore hybrids, having inherited one gene for yellow seeds (Y) and one for green seeds (y). All these progeny plants (the first filial, or F1, generation) have yellow seeds, so yellow (Y) is said to be dominant and green (y) recessive. The genotype (genetic composition) of the F1 peas is thus Yy, and their phenotype (physical appearance) is yellow. If one F1 offspring is bred with another, giving rise to F2 progeny, the genes for yellow and green seeds segregate in a characteristic manner such that the ratio between F2 plants with yellow seeds and those with green seeds is 3:1.
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