Question

.What are the pros and cons of the Gene Therapy Gendicine?​

Answer 1

Explanation:

Gendicine is a recombinant adenovirus engineered to express the tumor-suppressing gene p53 for patients with head and neck squamous cell carcinoma. It was approved by the Chinese Food and Drug Administration in 2003 When combined with chemotherapy and radiotherapy, gendicine can improve treatment efficacy 3.4-fold (a complete regression of tumors occurred in 64% of cases when gendicine was combined with radiotherapy as against 19% with radiotherapy alone) in addition to its ability to ameliorate any associated toxicity . Furthermore, gendicine has been shown to improve the therapeutic effect of radiation in pancreatic cancer cells . However, clinical trials in pancreatic cancer are yet to follow.