Question

What bonds hold together the Quaternary structure of protein?

Answer 1

Non-covalent and covalent bonds all contribute to the thermodynamics of protein folding.

• covalent bonds
• Ionic bonds
• hydrogen bonds
• ion-dipole bonds
• dipole dipole bonds
• van der walls forces
• and, the hydrophobic effect

For protein folding and quaternary structure the largest influence is the hydrophobic effect; which is the release of ordered water that occurs during protein folding.  This release of water significantly increases the entropy and drives the protein folding or Quaternary association.

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Answer 2

Answer :-

→ These chains are held together to form the larger protein by bonds that exist between the side groups of different chains.

→ As with tertiary structure, the bonds involved in holding these separate chains together can be van der Waals bonds, hydrogen bonds, ionic bonds, or at times covalent bonds.

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