what does BLUE BABY SYNDROME?
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Blue Baby Syndrome. Blue Baby Syndrome - An illness that begins when large amounts of nitrates in water are ingested by an infant and converted to nitrite by the digestive system. The nitrite then reacts with oxyhemoglobin (the oxygen-carrying blood protein) to form metheglobin, which cannot carry oxygen.
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Blue baby syndrome
Blue baby syndrome is a fatal condition.
It occurs when the hemoglobin (Fe2+) in an infant's red blood cells is oxidized to methemoglobin (Fe3+). Methemoglobin is unable to transport oxygen.
Affected infants develop an unusual blue-gray or lavender skin color.
Methemoglobin levels > 50% can quickly lead to coma and death if the condition is not recognized and treated.
The most common environmental agent associated with this condition is nitrate-contaminated water.
Infants are particularly susceptible to the condition during their first 6 months of life because they have low amounts of methemoglobin reductase, a red blood cell enzyme that converts methemoglobin back to hemoglobin.
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