what does various type of coated protein regulate endomembeane transport? drscribe with labelled diagram ? .......biology question
Answers
Transport processes mediate a continual exchange of components between the ten or more chemically distinct, membrane-enclosed compartments that collectively comprise the biosynthetic-secretory and endocytic pathways. In the presence of this massive exchange, how can each compartment maintain its specialized character? To answer this question, we must first consider what defines the character of a compartment. Above all, it is the composition of the enclosing membrane: molecular markers displayed on the cytosolic surface of this membrane serve as guidance cues for incoming traffic and ensure that transport vesicles fuse only with the correct compartment, thereby dictating the pattern of traffic between one compartment and another. Many membrane markers, however, are found on more than one organelle, and thus it is the specific combination of marker molecules that gives each organelle its unique molecular address.
Transport processes mediate a continual exchange of components between the ten or more chemically distinct, membrane-enclosed compartments that collectively comprise the biosynthetic-secretory and endocytic pathways. In the presence of this massive exchange, how can each compartment maintain its specialized character? To answer this question, we must first consider what defines the character of a compartment. Above all, it is the composition of the enclosing membrane: molecular markers displayed on the cytosolic surface of this membrane serve as guidance cues for incoming traffic and ensure that transport vesicles fuse only with the correct compartment, thereby dictating the pattern of traffic between one compartment and another. Many membrane markers, however, are found on more than one organelle, and thus it is the specific combination of marker molecules that gives each organelle its unique molecular address.We need to consider how patches of membrane, enriched or depleted in specific components, bud off from one compartment and transfer to another. In this section we describe how this is achieved. Some of the basic genetic and biochemical strategies that have been used to study the molecular machinery involved in vesicular transport .