Question

What happens when alkyl amide react with grignard reagent?

Answer 1

Answer:

For a N,N-alkyl, a N,N-diaryl or a N-alkyl-N-aryl amide that what will happen is that the grignard will react attacking the carbonyl carbon. ... One common method of making aldehydes is to react Grignards and other similar reagents with DMF, then treating the intial product with aqueous acid.

Answer 2

Answer:

Amides will react with three equivalents n-butyllithium to give nitriles via geminal lithium oxyimide intermediates (J. Org. ... For a N,N-alkyl, a N,N-diaryl or a N-alkyl-N-aryl amide that what will happen is that the grignard will react attacking the carbonyl carbon