what is abitch granual ? with function
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: a person (especially a man) who you strongly dislike or hate. —used to express surprise, disappointment, anger, etc. : something that is very difficult or unpleasant.
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Protease nexin-1 (PN-1) is a serpin that inhibits thrombin, plasmin and the plasminogen activators. PN-1 is barely detectable in plasma,124 but is produced by various cell types125 and is stored within the α-granules of platelets.126 PN-1 released from platelets during activation can downregulate both plasmin generation and plasmin activity on the fibrin surface.127 Platelet PN-1 has the capacity to inhibit both exogenous and endogenous tPA-mediated fibrinolysis.
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