what is cell cycle? Discuss the mechanism of its molecular control ?
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Explanation:
Positive Regulation of the Cell Cycle
Two groups of proteins, called cyclins and cyclin-dependent kinases (Cdks), are responsible for the progress of the cell through the various checkpoints. The levels of the four cyclin proteins fluctuate throughout the cell cycle in a predictable pattern
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What is cell cycle:
- A cell cycle is a series of events that takes place in a cell as it grows and divides.
- A cell spends most of its time in what is called interphase, and during this time it grows, replicates its chromosomes, and prepares for cell division.
- The cell then leaves interphase, undergoes mitosis, and completes its division.
Mechanism of its molecular control:
- Each step of the cell cycle is monitored by internal controls called checkpoints.
- There are three major checkpoints in the cell cycle: one near the end of G₁, a second at the G₂/M transition, and the third during metaphase.
- Positive regulator molecules allow the cell cycle to advance to the next stage.
- Negative regulator molecules monitor cellular conditions and can halt the cycle until specific requirements are met.
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