What is complement fixing antibodies biology discussion?
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During reaction, the complement binds to antigen-antibody complex and is used up or fixed. This process of complement fixation may be used to measure even very small amount of antibody that does not produce a visible reaction such as precipitation or agglutination. Therefore, it is necessary to use indicator system.
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In a reaction between an antigen with its cognate antibody present in serum, the complement disappears from the serum because of binding to the antigen-antibody complex. This is known as complement-fixation. ... A property of this antibody is that it can haemolyse sheep RBC in presence of complement.
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