What is coupling reaction tell me all about this
Answers
Explanation:
A coupling reaction in organic chemistry is a general term for a variety of reactions where two fragments are joined together with the aid of a metal catalyst. In one important reaction type, a main group organometallic compound of the type R-M (R = organic fragment, M = main group center) reacts with an organic halide of the type R'-X with formation of a new carbon-carbon bond in the product R-R'. The most common type of coupling reaction is the cross coupling reaction.[1][2][3]
Richard F. Heck, Ei-ichi Negishi, and Akira Suzuki were awarded the 2010 Nobel Prize in Chemistry for developing palladium-catalyzed cross coupling reactions.[4][5]
Broadly speaking, two types of coupling reactions are recognized:
Heterocouplings combine two different partners, such as in the Heck reaction of an alkene (RC=CH) and an alkyl halide (R'-X) to give a substituted alkene. Heterocouplings are called cross-couplings.
Homocouplings couple two identical partners, as in the Glaser coupling of two acetylides (RC≡CH) to form a dialkyne (RC≡C-C≡CR).
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Coupling reaction is the reaction in which, a compound gets attached to another, especially in the para position, through some part.
Check out the attachment, I'm providing with the reaction on how benzene diazonium salt is prepared from aniline, and the coupling reaction between aniline and benzene diazonium salt. The formation of a coloured dye takes place. Phenol too gives the coupling reaction with benzene diazonium salt.
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