Question

What is difference between thalasemia and sickle cell anemia??

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Answer 1

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Thalassaemia….. normally there is balanced 1:1 of alpha and beta chains in thalassaemia there is imbalance in globin chain leading to precipitation of globin chains within the RBCs leading to haemolysis

Sickle cell anaemia ….there is Hb s resulting from a single base mutation of adenine to thiamine resulting in Hb SS Hb AS common in Africa Middle East India south Europe there will be short life of RBCs

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Answer 2

thalasemia is the disease in which oxygen cant be recieved properly by haemoglobin and anaemia is the reproduction of immature and abnormal white blood cells