What is glycolysis ? Explain its steps.
Answers
Step 1:Hexokinase
Step 2:Phosphoglucose Isomerase
Step 3: Phosphofructokinase
Step 4: Aldolase
Step 5: Triphosphate isomera
Step 6: Glyceraldehyde-3-phosphate
Step 7: Phosphoglycerate Kinase
Step 8:PhosphoglycerateMutase
Step 9: Enolase
Step 10: Pyruvate Kinase
★ Glycolysis:-
→ It is the partial oxidation (breakdown) of glucose to O2 molecules of pyruvic acid in the absence of O2
→ It occurs in cytoplasm of all living organisms.
→ Its scheme (Greek glycos = sugar, lysis = splitting) was given by Gustav Embden, Otto Meyerhof & J. Parnas. So glycolysis is also known as EMP pathway.
→ In anaerobes, it is the only process in respiration.
→ In plants, glucose is derived from sucrose (end product of photosynthesis) or from storage carbohydrates.
→ Sucrose is converted into glucose & fructose by the enzyme, invertase. These two monosaccharides readily enter the glycolytic pathway.
→ Glucose & fructose are phosphorylated to form glucose-6-phosphate by the enzyme hexokinase. It is then isomerised to produce fructose-6-phosphate. Subsequent steps of metabolism of glucose and fructose are same.
★ Note:- Steps of glycolysis.
→ Look into the attechment for the steps of glycolysis.