What is helical loop?
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A basic helical -loop-helical is a protein structural motif that characterizes one of the largest families of dimerizing transcription factors. bHLH transcription factors are often important in development or cell activity. For one, BMAL1-Clock is a core transcription complex in the molecular circadian clock.
nitubarwal:
helical loop not helix loop
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- ʙᴀsɪᴄ ʜᴇʟɪcal-ʟᴏᴏᴘ-ʜᴇʟɪx ɪs ᴀ ᴘʀᴏᴛᴇɪɴ sᴛʀᴜᴄᴛᴜʀᴀʟ ᴍᴏᴛɪғ ᴛʜᴀᴛ ᴄʜᴀʀᴀᴄᴛᴇʀɪᴢᴇs ᴏɴᴇ ᴏғ ᴛʜᴇ ʟᴀʀɢᴇsᴛ ғᴀᴍɪʟɪᴇs ᴏғ ᴅɪᴍᴇʀɪᴢɪɴɢ ᴛʀᴀɴsᴄʀɪᴘᴛɪᴏɴ ғᴀᴄᴛᴏʀs. ʙʜʟʜ ᴛʀᴀɴsᴄʀɪᴘᴛɪᴏɴ ғᴀᴄᴛᴏʀs ᴀʀᴇ ᴏғᴛᴇɴ ɪᴍᴘᴏʀᴛᴀɴᴛ ɪɴ ᴅᴇᴠᴇʟᴏᴘᴍᴇɴᴛ ᴏʀ ᴄᴇʟʟ ᴀᴄᴛɪᴠɪᴛʏ. ғᴏʀ ᴏɴᴇ, ʙᴍᴀʟ1-ᴄʟᴏᴄᴋ ɪs ᴀ ᴄᴏʀᴇ ᴛʀᴀɴsᴄʀɪᴘᴛɪᴏɴ ᴄᴏᴍᴘʟᴇx ɪɴ ᴛʜᴇ ᴍᴏʟᴇᴄᴜʟᴀʀ ᴄɪʀᴄᴀᴅɪᴀɴ ᴄʟᴏᴄᴋ.
@αρσσɾѵαɦεɾε
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