Question

what is isotopic effect ?​

Answer 1

physical organic chemistry, a kinetic isotope effect (KIE) is the change in the reaction rate of a chemical reaction when one of the atoms in the reactants is replaced by one of its isotopes.

Answer 2

Answer:

In physical organic chemistry, a kinetic isotope effect (KIE) is the change in the reaction rate of a chemical reaction when one of the atoms in the reactants is replaced by one of its isotopes.[3] Formally, it is the ratio of rate constants for the reactions involving the light (kL) and the heavy (kH) isotopically substituted reactants (isotopologues):

{\displaystyle {\text{KIE}}={\frac {k_{L}}{k_{H}}}}{\displaystyle {\text{KIE}}={\frac {k_{L}}{k_{H}}}}