Question

what is main reason of erythroblsdtosis foetails

Answer 1

reason behind this is the mixture of feotus blood with that of the mother during parturation .
mother's body started producing antigens.

Answer 2

NEWSLETTER


Erythroblastosis Fetalis
Medically reviewed by Steven Kim, MD on July 7, 2015 — Written by Rachel Nall, RN, BSN on July 7, 2015
Causes
Diagnosis
Symptoms
Treatment
Outlook
What Is Erythroblastosis Fetalis?
The adult human body is home to trillions of red blood cells (also known as erythrocytes or RBCs). These blood cells carry oxygen, iron, and many other nutrients to the appropriate places in the body. When a woman is pregnant, it’s possible that her baby’s blood type will be incompatible with her own. This can cause a condition known as erythroblastosis fetalis, where the mother’s white blood cells attack the baby’s red blood cells as they would any foreign invaders.

Also known as hemolytic disease of the newborn, this condition is highly preventable. Catching it early can ensure a successful pregnancy for mother and child. If left untreated, this condition can be life-threatening for the baby.


CAUSES
What Causes Erythroblastosis Fetalis?
There are two main causes of erythroblastosis fetalis: Rh incompatibility and ABO incompatibility. Both are associated with blood type. There are four blood types: A, B, AB, and O. And blood can be either Rh positive or Rh negative. If a person is type A and is Rh positive, they have A antigens and the Rh factor antigens on the red blood cell membrane surface. If a person has AB negative blood, they have both A and B antigens without the Rh factor antigen.

Rh Incompatibility
Rh incompatibility occurs when an Rh-negative mother is impregnated by an Rh-positive father. The result can be an Rh-positive baby. In such a case, the baby’s Rh antigens will be perceived as foreign invaders, the way viruses or bacteria are perceived. The mother’s blood cells attack the baby’s as a protective mechanism that can end up harming the child.

If the mother is pregnant with her first baby, Rh incompatibility is not as much of a concern. However, when the Rh-positive child is born, the mother’s body creates antibodies against the Rh factor, which will attack the blood cells if she becomes pregnant with another Rh-positive baby.

ABO Incompatibility
Another type of hemolytic disease of newborns is ABO blood type incompatibility. This occurs when the mother’s blood type of A, B, or O is not compatible with the baby’s. This condition is considered less harmful or threatening to the baby than Rh incompatibility. However, babies can carry rare antigens that can put them at risk for erythroblastosis fetalis. These antigens include:

Kell
Duffy
Kidd
Lutheran
Diego
Xg
P
Ee
Cc
MNSs