what is mannich reaction
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The Mannich Reaction is an orangic reaction which consists of an amino alkylation of an acidic proton placed next to a carbonyl functional group by formaldehyde and a primary or secondary amine or ammonia. The final product is a B-amino-carbonyl compound also known as Mabnich Base.
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MANNICH REACTION
- The Mannich reaction in organic chemistry is a three-component organic reaction that encompasses the amino alkylation of an acidic proton after to a carbonyl (C=O) functional group by formaldehyde (H−CHO) and a primary or secondary amine or ammonia.
- The ultimate product is a β-amino-carbonyl compound which is also known as a Mannich base.
- Reactions between aldimines and α-methylene carbonyls are also deemed as Mannich reactions the reason is that these imines form between amines and aldehydes.
- The Mannich reaction is titled after Carl Mannich.
- The Mannich reaction is the organic reaction where an acidic proton, which is placed next to a carbonyl group, withstands an amino alkylation with the support of formaldehyde and ammonia
- Mannich reaction means starts with the arrangement of an iminium ion from the reaction between formaldehyde and amine.
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