What is meant by interfernce in genetics?
Answers
Answered by
2
DNA segment with three genes, showing a double recombination event. If the individual recombination rates (between A and B; and between B and C) are known, then the c.o.c. between the regions AB and BC can be calculated from the rate of double recombination.
In genetics, the coefficient of coincidence (c.o.c.) is a measure of interference in the formation of chromosomal crossovers during meiosis. It is generally the case that, if there is a crossover at one spot on a chromosome, this decreases the likelihood of a crossover in a nearby spot.[1] This is called interference.
The coefficient of coincidence is typically calculated from recombination rates between three genes. If there are three genes in the order A B C, then we can determine how closely linked they are by frequency of recombination. Knowing the recombination rate between A and B and the recombination rate between B and C, we would naively expect the double recombination rate to be the product of these two rates.
The coefficient of coincidence is calculated by dividing the actual frequency of double recombinants by this expected frequency:[1]
c.o.c. = actual double recombinant frequency / expected double recombinant frequency
Interference is then defined as follows:[1]
interference = 1 − c.o.c.
This figure tells us how strongly a crossover in one of the DNA regions (AB or BC) interferes with the formation of a crossover in the other region.
Pls mark it as brainliest
In genetics, the coefficient of coincidence (c.o.c.) is a measure of interference in the formation of chromosomal crossovers during meiosis. It is generally the case that, if there is a crossover at one spot on a chromosome, this decreases the likelihood of a crossover in a nearby spot.[1] This is called interference.
The coefficient of coincidence is typically calculated from recombination rates between three genes. If there are three genes in the order A B C, then we can determine how closely linked they are by frequency of recombination. Knowing the recombination rate between A and B and the recombination rate between B and C, we would naively expect the double recombination rate to be the product of these two rates.
The coefficient of coincidence is calculated by dividing the actual frequency of double recombinants by this expected frequency:[1]
c.o.c. = actual double recombinant frequency / expected double recombinant frequency
Interference is then defined as follows:[1]
interference = 1 − c.o.c.
This figure tells us how strongly a crossover in one of the DNA regions (AB or BC) interferes with the formation of a crossover in the other region.
Pls mark it as brainliest
Attachments:
Similar questions