Question

what is nephron and what is its function

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A nephron is the basic unit of structure in the kidney. A nephron is used separate to water, ions and small molecules from the blood, filter out wastes and toxins, and return needed molecules to the blood. The nephron functions through ultrafiltration. Ultrafiltration occurs when blood pressure forces water and other small molecules through tiny gaps in capillary walls. This substance, lacking the blood cells and large molecules in the bloodstream, is known as an ultrafiltrate. The ultrafiltrate travels through the various loops of the nephron, where water and important molecules are removed, and into a collecting duct which drains into the bladder.


The glomerulus is the specialized configuration of capillaries within the nephron that make kidneys possible. Vertebrates are the only group to have developed kidneys, which is mostly used to conserve water in terrestrial environments. Fish and other primitive vertebrates excrete ammonia as a byproduct of protein reactions. Ammonia is toxic in the bloodstream, and must be removed. Reptiles and birds excrete uric acid, which is a more concentrated form of ammonia. Mammals have even more derived nephrons, which contain an extended loop, called the loop of Henle. Mammals produce urea from ammonia, and concentrate the urea in the urine to a high extent. This promotes the extraction of water from the ultrafiltrate, and allows mammals to live in some of the driest environments on Earth. A camel, for instance, will continually filter most of the water from its blood, recollect a large majority of that water, and reuse it continually.

Function of a Nephron

A nephron is responsible for removing waste products, stray ions, and excess water from the blood. The blood travels through the glomerulus, which is surrounded by the glomerular capsule. As the heart pumps the blood, the pressure created pushes small molecules through the capillaries and into the glomerular capsule. This is the, more physical function of the nephron. Next, the ultrafiltrate must travel through a winding series of tubules. The cells in each part of the tube have different molecules that they like to absorb. Molecules to be excreted remain in the tubule, while water, glucose and other beneficial molecules work their way back into the bloodstream. As the ultrafiltrate travels down the tubules, the cells become more and more hypertonic compared to the ultrafiltrate. This causes a maximum amount of water to be extracted from the ultrafiltrate before it exits the nephron. The blood surrounding the nephron returns to the body via the interlobular vein, free of toxins and excess substances. The ultrafiltrate is now urine, and moves via the collecting duct to the bladder, where it will be stored.



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