what is pepsonogen anser in brife more than 100 words
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Answer:Listen to pronunciation. (pep-SIH-noh-jen) A substance made by cells in the stomach. Acid in the stomach changes pepsinogen to pepsin, which breaks down proteins in food during digestion.
Pepsinogen is a powerful and abundant protein digestive enzyme secreted by the gastric chief cells as a proenzyme and then converted by gastric acid in the gastric lumen to the active enzyme pepsin. The role of pepsin and its precursor in protein digestion was first described in the 19th century.
Pepsinogen is activated in the stomach lumen by hydrolysis, with the removal of a short peptide: H+ ions are important for pepsin function because: Pepsinogen is initially activated by the H+ ions. The activated enzyme then acts autocatalytically to increase the rate of formation of more pepsin.