what is ratio of phenylketonuria... please tell me frnds
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For phenylalanine only screening, the number of presumptive positive is 15.6 per 1000 borns when the ratio is used, the number of positive is 3.9 per 10,000
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In this study, 37% of the newborns were tested at less than 24 hours of age. For this population, using a phenylalanine only cut off of 200 mumol/l, there were 48 recalled infants per case of classic PKU. Using the phenylalanine:tyrosine ratio with a cut off of 1.50, screen positives could be reported with phenylalanine as low as 150 mumol/l and with only 12 recalls per case.
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