What is recombinant DNA vaccine? Give two examples.
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Recombinant DNA vaccine is the one that has been formed with the help of recombinant DNA and contains onlyimmunogenic protein or other biochemical which causes development of antibodies against the disease. Example: Hepatitis B, Influenza B and Meningitis.
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Answer:
- Recombinant DNA technology has allowed the production of antigenic polypeptides of pathogen in bacteria and yeast.
- Vaccines produced using this approach allow large scale production and hence greater availability for immunisation.
- Vaccine prepared by rDNA technology are rDNA vaccine.
Examples:
- Hepatitis-B vaccine produced from yeast.
- Herpes simplex virus vaccine.
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