Question

what is role of centromsomes in animal cell​

Answer 1

Answer:

centrosomes also known as centrioles..are responsible for regulation of cell division cycle

Answer 2

Centrosome function and assembly in animal cells

• Centrosomes are not essential for cell division in most animal cells, although they contribute to the efficiency of mitotic spindle assembly.

• Centrosome loss is tolerated surprisingly well in fly cells, but it normally induces a p53-dependent block to proliferation or apoptosis in vertebrate cells.

• Centrosome dysfunction in humans may promote cancer by increasing levels of chromosomal instability and/or the metastatic potential of cancer cells, although strong genetic evidence for this link is lacking.

• Strong genetic evidence links centrosome dysfunction to microcephaly and primordial dwarfism in humans, although the reasons for this link are unclear.

• There have been dramatic recent advances in our molecular understanding of how centrioles and centrosomes assemble.

• In flies and in worms, the SPD2 and Polo or Polo-like kinase 1 (PLK1) proteins cooperate with Cnn (in flies) or SPD-5 (in worms), to drive the assembly of a scaffold structure around the mother centriole during mitosis that functions to recruit other proteins to the mitotic centrosome.

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