Question

what is the advantages of waterproof wall of ascending limb of Henle's loop​

Answer 1

Answer:

The ascending limb (where loop diuretics work) is impermeable to water. NaCl is pumped from the tubule into the interstitium in the ascending limb. The tubular osmolarity decreases and fluid that leaves the loop is hypotonic. The collecting duct is impermeable to water without ADH.