What is the difference between allosteric and non-competitive inhibition?
Answers
Answer:
Explanation:Allosteric inhibition is the type of enzymatic regulation where the inhibitor binds to a site other than the active site. ... Non-competitive inhibition is when the inhibitor inhibits the enzymatic reaction whether or not the substrate is bound to it. It can bind to a site other than the active site and can be allosteric
Some characteristics of Non- competitive Inhibition are as follows :-
(i) This type of Inhibitor do not block the substrate molecules.
(ii) They bind to a site but they never bind to an active site.
(iii) Conformational change is the result of binding of the inhibitor to any enzyme's active site.
(iv) As a result of the confirmational change, both the active site and substrate doesn't share any type of specificity, hence now the substrate cannot bind.
Some features of Allosteric Inhibition are as follows :-
(i) Allosteric means other site.
(ii) Such enzymes are having two receptor sites.
(iii) One of the two site fits the substrate like other enzyme and other site fits to an inhibitor.
(iv) In this accumulation of the last product of the reaction is able to inhibiting the step of reaction.