what is the difference between proteins translated by free ribosome and protein translated by ribosome attached to endoplasmic reticulem?
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While a structure such as a nucleus is only found in eukaryotes, every cell needs ribosomes to manufacture proteins. Since there are no membrane-bound organelles in prokaryotes, the ribosomes float free in the cytosol. Endoplasmic reticulum with attached ribosomes is called rough ER. It looks bumpy under a microscope.
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