What is the function of PCT ?
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Absorption. The proximal tubule efficiently regulates the pH of the filtrate by exchanging hydrogen ions in the interstitium for bicarbonate ions in the filtrate; it is also responsible for secreting organic acids, such as creatinine and other bases, into the filtrate.
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The function of the proximal tubule is essentially reabsorption of filtrate in accordance with the needs of homeostasis (equilibrium), whereas the distal part of the nephron and collecting duct are mainly concerned with the detailed regulation of water, electrolyte, and hydrogen-ion balance.
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