what is the life cycle of plasmodium
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LiFe CYcLe Of PlaSmoDium :
1. Sporozoites: The infectious form of Plasmodium which enters the human body through the bite of a female Anopheles mosquito.
2. Multiplication of parasites inside the liver cells.
3. Attack of the RBCs by the parasites causing the rupture of the RBCs.
4. Release of a toxic substance called haemozoin by the ruptured RBCs that causes chills and recurring fevers every three to four days.
5. Transfer of the parasites into the body of the female Anopheles mosquito when the infected person is bitten by the mosquito.
6. Multiplication of the parasites within the mosquito to form sporozoites. These sporozoites are stored in the salivary glands of the mosquito.
7. The infected mosquito bites an uninfected person and the cycle repeats.
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- The vector, the Anopheles species mosquito, transmits plasmodia, which are contained in its saliva, into its host while obtaining a blood meal.
- Plasmodia enter circulating erythrocytes (red blood cells, or RBCs) and feed on the hemoglobin and other proteins within the cells.
- One brood of parasites becomes dominant and is responsible for the synchronous nature of the clinical symptoms of malaria.
- Malaria-carrying female Anopheles species mosquitoes tend to bite only between dusk and dawn.
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