Question

What is the major end product of oxidation of aromatic carbon atoms?

Answer 1

Answer:

The oxidation of aromatic carbon atoms proceeds via formation of a reactive intermediate arene oxide.

Answer 2

The major end product of oxidation of aromatic carbon atoms is arenol metabolites.

Explanation:

• Hydroxylation results in the formation of arenol metabolites when an aromatic compound is oxidised.
• The cytochrome P450 enzymes produce an epoxide intermediate called 'arene oxide,' which is then followed by the NIH shift or the 1,2-hydride shift for most aromatic compounds.
• Non-cleavage of the aromatic ring, cleavage of the aromatic ring, and  oxidation of the side chains connected to the aromatic ring are all examples of aromatic oxidation.  
• The synthesis of oxygenates without cleavage of the aromatic rings, such as phenol or benzoquinone from benzene.