What is the most accurate measurement of glomerular filtration rate?
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Glomerular filtration rate (GFR) describes the flow rate of filtered fluid through the kidney. Creatinine clearance rate (CCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR.
Glomerular filtration rate (GFR) describes the flow rate of filtered fluid through the kidney. Creatinine clearance rate (CCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR.
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Assessment of GFR is essential to accurately diagnose kidney disease. GFR is difficult and impractical to measure directly with current methodologies, and estimates of GFR by serum creatinine and/or cystatin C are most accurate once GFR is <60ml/min/1.73m2, a point at which half of renal function is already lost.
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