*What is the name of FIRST Restriction Endonuclease Enzyme?* 1️⃣ Hind II 2️⃣ EcoRY 13 3️⃣ pBR 322 4️⃣ Hind II BX
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In 1970, Hamilton-Smith and his coworkers first isolated a restriction enzyme from the bacterium Haemophilus Influenzae and named it HindII which recognizes a six pair ds DNA sequence.
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(1️) Hind II is the first endonuclease enzyme.
Explanation:
- The restriction endonuclease HINDI II. A restriction enzyme, also known as a restriction endonuclease, is an enzyme that cleaves DNA into pieces at or near restriction sites within the molecule.
- Endonucleases from various bacteria identify nucleotide sequences and cleave DNA at distinct cleavage sites as a result. Restriction enzymes can be divided into two groups. Type II enzymes make up Class 1. Type I and type II enzymes make up class II enzymes.
- The restriction enzyme HindII was the first to be discovered by Hamilton O. Smith. This enzyme was discovered in Haemophilus influenzae Rd strain II for the first time. As a result, HindII was assigned to the enzyme. It is the first site-specific restriction endonuclease.
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