Question

What is the utility of feedback operated by hormone?

Answer 1

Primary GH deficiency (GHD) results in normal birth size but, when untreated, adult final height is severely compromised [4] . A peak GH concentration of less than 10 ng/mL following stimulation by one or more secretagogues and assayed by RIA has traditionally been used to support the diagnosis of GHD [5]. Treatment with exogenous rhGH began in 1985 and has become a well-accepted therapeutic option for children with growth failure caused by GHD, as well as many other condi- tions [6] .