What reagents are used for birch reduction?
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Na with liquid ammonia or lithium with liquid ammonia
Krishnatripathi:
Is it syn or anti
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Answer:
The reagents used for Birch reduction are sodium and liquid ammonia.
Explanation:
Birch reduction is used for the reduction of a benzenoid ring to 1,4 cyclohexadiene by treating the benzenoid ring with lithium or sodium metal in liquid ammonia and ethanol, which is a proton source. Here, all double bonds are not reduced. Selective reduction of double bonds takes place in Birch reduction.
In Birch reduction, electron-donating groups are mainly found at the non-reduced positions of the product, whereas electron-withdrawing groups are at the reduced positions of the product.
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