what was Mr Otto Frank's major contribution to the world?
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Neharika asked in English
What was Otto Frank's major contribution to the world
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G Vijaychithra answered this
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Frank's initial research was related to fat absorption. But in his postdoctoral work (Habilitationsschrift) Frank investigated the isometric and isotonic contractile behaviour of the heart and it is this work that he is best known for. Frank's work on this topic preceded that of Ernest Starling, but both are usually credited with providing the foundations of what is termed the Frank–Starling law of the heart. This law states that "Within physiological limits, the force of contraction is directly proportional to the initial length of the muscle fiber". Frank also undertook important work into the physiological basis of the arterial pulse waveform and may have coined the term essential hypertension in 1911.[5] His work on the Windkessel extended the original ideas of Stephen Hales and provided a sound mathematical framework for this approach. Frank also published on waves in the arterial system but his attempts to produce a theory that incorporated waves and the Windkessel are not considered to have been successful. Frank also did work on the oscillatory characteristics of the auditory apparatus of the ear and the thermodynamics of muscle. He also worked extensively on developing accurate methods to measure blood pressure and other physiological phenomena
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Neharika asked in English
What was Otto Frank's major contribution to the world
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G Vijaychithra answered this
9 helpful votes in English, Class X
Frank's initial research was related to fat absorption. But in his postdoctoral work (Habilitationsschrift) Frank investigated the isometric and isotonic contractile behaviour of the heart and it is this work that he is best known for. Frank's work on this topic preceded that of Ernest Starling, but both are usually credited with providing the foundations of what is termed the Frank–Starling law of the heart. This law states that "Within physiological limits, the force of contraction is directly proportional to the initial length of the muscle fiber". Frank also undertook important work into the physiological basis of the arterial pulse waveform and may have coined the term essential hypertension in 1911.[5] His work on the Windkessel extended the original ideas of Stephen Hales and provided a sound mathematical framework for this approach. Frank also published on waves in the arterial system but his attempts to produce a theory that incorporated waves and the Windkessel are not considered to have been successful. Frank also did work on the oscillatory characteristics of the auditory apparatus of the ear and the thermodynamics of muscle. He also worked extensively on developing accurate methods to measure blood pressure and other physiological phenomena
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Otto Frank was the father of Anne Frank. He was the one responsible for the publication of the Anne diary. In 1933 when Hitler came into power, Otto Frank along with his wife and two daughters escaped Nazi Germany. They lived peacefully in Amsterdam. But in 1940 when Nazi Germany invaded the Netherlands, their life came upside down. He was the only annex resident to survive the evils of the Holocaust. When he got Anne's diary he decided to publish it as 'The Secret Annex' in 1947.
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