Question

what will happen if the receptor sites on the post synaptic membrane are blocked by drug at the neuromuscular junction?
(A) inhibition of acetylcholine
(B)muscle contraction
(C)inhibition of cholinesterase
(D)muscle paralysis

Answer 1

Answer:

Muscle paralysis

Explanation:

Hint for every option

❌. A option because release of neurotransmitters are related to arrival of action potential at pre synaptic cleft and it is not related to blockage of receptor of post synaptic cleft

❌.B option muscle contraction also wrong because muscle contraction result from passage of action potential . so here receptor site are blocked so no impulse pass therefore no muscle contraction occur

❌.C option wrong because release or inhibition of enzymes are not related to blockage of receptor on post synaptic cleft

✅.D muscle paralysis correct

because no impulse of adequate or threshold stimulus get pass through post synaptic cleft as a result of blockage of receptor as a result muscle paralysis occured means muscle would be unable to contract or relax and remain static

Answer 2

If the receptor sites on the post-synaptic membrane are blocked by the drug at the neuromuscular junction, then (D) muscle paralysis will occur.

• Due to the blockage of the receptor sites, the neurotransmitters will not be able to bind with the particular receptor sites at the post-synaptic membrane.
• The neuromuscular junction is defined as a connection established through synapses between the muscle and the motor nerve's terminal.
• Due to the inability of the neurotransmitters to bind, no stimuli will set across the membrane that would operate movement. This leads to serious damages like muscle paralysis.

Hence, the correct answer will be (D) muscle paralysis occurs when the receptor sites on the post-synaptic membrane are blocked by a drug at the neuromuscular junction.

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