Question

What will happen if the secretion of parietal cells
of gastric glands is blocked with an inhibitor?
(a) Gastric juice will be deficient in chymosin
(b) Gastric juice will be deficient in pepsinogen
(c) In the absence of HCI secretion, inactive
pepsinogen is not converted into the active
enzyme pepsin
(d) Enterokinase will not be released from the
duodenal mucosa and so trypsinogen is not
converted to trypsin

Answer 1

Answer:

(b) gastric juice will be deficient in pepsinogen

Answer 2

If the secretion of parietal cell in gastric juice is blocked:

• Option “C” is correct i.e. in the absence of HCI secretion, inactive

pepsinogen is not converted into the active

enzyme pepsin.

• If the secretion of parietal cells of gastric juice is blocked with an inhibitor, in the absence of Hydrochloric acid secretion, inactive pepsinogen is not transformed into pepsin.

• Gastric glands are mini tubular glands made by the epithelial cells of the stomach in which parietal cell is present on the sidewalls of the gastric glands. These cells discharge a hydrochloric acid and fortress intrinsic factor which upholds a strongly acidic pH of about 1.5 - 2.0 in the stomach. HCl converts the pepsinogen to pepsin and rennin correspondingly. If we blocked the parietal cells' secretion with an inhibitor, inactive pepsinogen is not transformed into the active pepsin.

Hope it helped....